{"id":239355,"date":"2025-09-27T05:25:00","date_gmt":"2025-09-27T09:25:00","guid":{"rendered":"https:\/\/props.com\/?p=239355"},"modified":"2025-09-27T06:20:27","modified_gmt":"2025-09-27T10:20:27","slug":"cfb-week-5-picks-expert-predictions-preview","status":"publish","type":"post","link":"https:\/\/props.com\/cfb-week-5-picks-expert-predictions-preview\/","title":{"rendered":"CFB Week 5 Predictions: Expert Picks &amp; Preview"},"content":{"rendered":"\n<p>Welcome to our College Football Week 5 predictions! We&#8217;ll look at the top games of the day and what that means for our favorite CFB picks and player props.<\/p>\n\n\n\n<p>Check our <a href=\"https:\/\/props.com\/league\/ncaaf\/\">NCAAF News Hub <\/a>for all things Week 5!<\/p>\n\n\n    <div class=\"au_outer_wrap column_count_3 has_title au_format_mobile_table au_table_state_GA a_unit au_template-2 mobile_table au_template-2c au_type_sportsbook,fantasy\">\n        <div class=\"au_table_wrap\">\n                            <h2 class=\"au_table_title\">Top Betting Apps in All States<\/h2>\n                        <div class=\"au_table\">\n                    <div class=\"two_c_row\">\n        <div class=\"au_row au_table_row_1 offer_id-1\" style=\"position:relative;\">\n            <a\n                href=\"\/go\/draftkings?src=wp-json%2Fwp%2Fv2%2Fposts%2F239355\"\n                target=\"_blank\"\n                rel=\"noopener nofollow\"\n                aria-label=\"Draftkings Sportsbook\"\n                                    class=\"card-cover-link offer_id-1 au_table_row_1\"\n                                data-offer-id=\"1\"\n                style=\"position:absolute; inset:0; z-index:1; display:block; text-decoration:none; color:inherit;\"><\/a>\n\n            <div class=\"au_col au_col_logo \">\n                                <img decoding=\"async\"\n                     width=\"100\" height=\"100\"\n                     src=\"https:\/\/props.com\/wp-content\/uploads\/2025\/06\/dklogosbk.png\"\n                     class=\"attachment-amaff-small size-amaff-small\"\n                     alt=\"Draftkings Sportsbook\"\n                     srcset=\"https:\/\/props.com\/wp-content\/uploads\/2025\/06\/dklogosbk.png 200w, https:\/\/props.com\/wp-content\/uploads\/2025\/06\/dklogosbk-150x150.png 150w, https:\/\/props.com\/wp-content\/uploads\/2025\/06\/dklogosbk-90x90.png 90w, https:\/\/props.com\/wp-content\/uploads\/2025\/06\/dklogosbk-180x180.png 180w, https:\/\/props.com\/wp-content\/uploads\/2025\/06\/dklogosbk-330x330.png 330w, https:\/\/props.com\/wp-content\/uploads\/2025\/06\/dklogosbk-660x660.png 660w\"\n                     sizes=\"(max-width: 100px) 100vw, 100px\" \/>\n            <\/div>\n\n            <div class=\"au_col au_col_title-bonus\">\n                <div class=\"au_subfield au_col_title\">\n                                            <a href=\"https:\/\/props.com\/review\/draftkings-sportsbook\/\" target=\"_blank\" rel=\"noopener nofollow\">Draftkings Sportsbook<\/a>\n                                    <\/div>\n                <div class=\"au_subfield au_col_bonus\">\n                    <div class=\"au_bonus\">\n                        <span class=\"tablet-landscape-up-only\">\n                            <div class=\"au_bonus_line au_bonus_line_1 a-class\">\n                                Bet $5+, Get $200 If Your Bet Wins                            <\/div>\n                            <div class=\"au_bonus_line au_bonus_line_2 a-class\">\n                                NO PROMO CODE NEEDED                            <\/div>\n                        <\/span>\n                        <span class=\"up-to-tablet-landscape-only\">\n                            <div class=\"au_bonus_line au_bonus_line_1 a-class\">\n                                Bet $5+, Get $200 If Your Bet Wins                            <\/div>\n                            <div class=\"au_bonus_line au_bonus_line_2 a-class\">\n                                NO PROMO CODE NEEDED                            <\/div>\n                        <\/span>\n                    <\/div>\n                <\/div>\n            <\/div>\n            <div class=\"au_col au_col_bonus_code-button\" style=\"position:relative; z-index:2;\">\n                \n                <div class=\"au_subfield au_col_button\">\n                    <a href=\"\/go\/draftkings?src=wp-json%2Fwp%2Fv2%2Fposts%2F239355\"\n                       target=\"_blank\"\n                       rel=\"noopener nofollow\"\n                       class=\"button au_button play_now small\">\n                        <span class=\"up-to-tablet-landscape-only\">CLAIM OFFER<\/span>\n                        <span class=\"tablet-landscape-up-only\">CLAIM OFFER<\/span>\n                    <\/a>\n                <\/div>\n            <\/div>\n        <\/div>\n\n                    <div class=\"cau_disclaimer_text\">\n                <span class=\"clamped-text\">\n                  GAMBLING PROBLEM? 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This promotional offer is not available in DC, Mississippi, New York, Nevada, Ontario, or Puerto Rico.                 <\/span>\n                <button type=\"button\" class=\"read-more\"> See more\u2026<\/button>\n            <\/div>\n            <\/div>\n                <\/div>\n        <\/div>\n    <\/div>\n    \n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-college-football-week-5-predictions-amp-preview\">College Football Week 5 Predictions &amp; Preview<\/h2>\n\n\n\n<p>We\u2019re into Week 5\u2014the last weekend of September\u2014and while the first month hasn\u2019t seen too many shocking shake-ups, the table is set for a major shake this Saturday. <\/p>\n\n\n\n<p>The AP poll\u2019s top 9 teams are still unbeaten, but with several ranked-vs-ranked matchups and road challenges for contenders, that\u2019s about to change. This week finally delivers the heavyweight battles fans have been waiting for.<\/p>\n\n\n\n<p><em>Reminder: all picks below are based on opening lines available Thursday. Check your sportsbook for updated numbers\u2014late movement could shift things before kickoff.<\/em><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Friday Night Spotlight<\/h3>\n\n\n\n<p><strong>No. 8 Florida State at Virginia (ESPN, 7 p.m.)<\/strong> &#8211; FSU opened the season by shocking Alabama and has steamrolled lesser opponents since (two 65+ point outbursts). Virginia, 3\u20131, is scrappy but dropped a close one to NC State. Florida State has Miami looming next week, so expect a focused tune-up. <em><strong>Pick<\/strong>: Florida State (-6) to handle business on the road in this ACC clash.<\/em><\/p>\n\n\n\n<p><strong>No. 24 TCU at Arizona State (9 p.m., ESPN2)<\/strong> &#8211; TCU has been shaky late in games, letting SMU hang around last week. Meanwhile, ASU is off a gritty three-point road win (almost half their points were via field goal) at Baylor and returns home under the Friday night lights. Momentum and home energy tilt this one toward Tempe. <em><strong>Pick<\/strong>: Arizona State ML pulls the upset in a tight one.<\/em><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-saturday-slate-noon-kickoffs\">Saturday Slate &#8211; Noon Kickoffs<\/h3>\n\n\n\n<p><strong>No. 16 Georgia Tech at Wake Forest (ESPN)<\/strong> &#8211; Haynes King has been a dual-threat revelation\u2014five rushing TDs already\u2014and the Yellow Jackets look like a legit ACC dark horse. Wake hasn\u2019t faced a real test yet. <em><strong>Pick<\/strong>: Georgia Tech rolls, King strengthens his quiet Heisman case.<\/em><\/p>\n\n\n\n<p><strong>No. 21 USC at No. 23 Illinois (FOX Big Noon)<\/strong> &#8211; USC QB Jayden Maiava is averaging 10 yards per completion and has nine TDs with no picks. Illinois? Just got shredded by Indiana, allowing 63 points. The Illini defense isn\u2019t Playoff-caliber, they are pretenders and won\u2019t be ranked next week. <em><strong>Pick<\/strong>: USC ML.<\/em><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Afternoon Showdowns (3:30 p.m.)<\/h3>\n\n\n\n<p><strong>No. 1 Ohio State at Washington (CBS)<\/strong> &#8211; Ohio State QB Julian Sayin is passable (7 TDs, 3 INTs) but hasn\u2019t looked untouchable. Washington has quietly put up 38+ in every game and QB Demond Williams Jr. is electric, averaging 73% completions. Huskies won\u2019t back down at Husky Stadium. <em><strong>Pick<\/strong>: Washington keeps it close, OSU squeaks out a win after their bye week.<\/em><\/p>\n\n\n\n<p><strong>No. 4 LSU at No. 13 Ole Miss (ABC)<\/strong> &#8211; Great ranked matchup. Biggest storyline? Off the field, Lane Kiffin\u2019s daughter announced a relationship with LSU linebacker Whit Weeks. Lane tweeted take the over. I\u2019m listening to coach <em><strong>Pick<\/strong>: OVER<\/em><\/p>\n\n\n\n<figure class=\"wp-block-embed aligncenter is-type-rich is-provider-twitter wp-block-embed-twitter\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"twitter-tweet\" data-width=\"500\" data-dnt=\"true\"><p lang=\"en\" dir=\"ltr\">Take the over \ud83c\udfc8<\/p>&mdash; Lane Kiffin (@Lane_Kiffin) <a href=\"https:\/\/twitter.com\/Lane_Kiffin\/status\/1970314061259612227?ref_src=twsrc%5Etfw\">September 23, 2025<\/a><\/blockquote>\n<\/div><\/figure>\n\n\n\n<p><strong>No. 11 Indiana at Iowa (FOX)<\/strong> &#8211; Transfer QB Fernando Mendoza has lit it up\u201414 TDs, no picks\u2014and looks like a real Heisman name. Iowa\u2019s defense isn\u2019t its usual elite form and got gashed by Rutgers last week for 28 points <em><strong>Pick<\/strong>: Indiana (-8.5) to stay unbeaten.<\/em><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Prime-Time Blockbusters (7:30 p.m.)<\/h3>\n\n\n\n<p><strong>No. 6 Oregon at No. 3 Penn State (ABC)<\/strong> &#8211; This is the White Out game, and Beaver Stadium will be wild. But history isn\u2019t kind to James Franklin (just 4\u201320 vs. AP top-10 teams). Oregon\u2019s freshman QB Dante Moore has handled every test so far, and PSU\u2019s Drew Allar has looked shaky in spots. <em><strong>Pick<\/strong>: Oregon +3.5 to cover, with real upset potential.<\/em><\/p>\n\n\n\n<p><strong>No. 17 Alabama at No. 5 Georgia (CBS)<\/strong> &#8211; Ty Simpson has turned Alabama\u2019s offense around the last two weeks, but the Tide were pushed around by Florida State in Week 1. Georgia has been leaky defensively (Tennessee dropped 41 on them), so expect points. At home, the Bulldogs should edge it. <em><strong>Pick<\/strong>: Georgia wins, but the safer bet is the over (53.5).<\/em><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Quick Hits &amp; Storylines<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Heisman Watch<\/strong>: Fernando Mendoza (Indiana) is now the frontrunner after dismantling Illinois. Haynes King (Georgia Tech) lurks as a sleeper.<br \/><\/li>\n\n\n\n<li><strong>SEC Wildcards<\/strong>: Auburn\u2013Texas A&amp;M and LSU\u2013Ole Miss could define the league\u2019s middle tier and the Playoff race.<br \/><\/li>\n\n\n\n<li><strong>Upset Radar<\/strong>: Arizona State on Friday night, Washington in the afternoon, and Ole Miss all have realistic paths to big-time statement wins.<br \/><\/li>\n<\/ul>\n\n\n\n<p>That\u2019s the Week 5 rundown: marquee games finally on deck, Heisman contenders emerging, and unbeaten giants walking into real danger. Buckle up\u2014the last week of September could be the one that rewrites the Playoff picture.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Welcome to our College Football Week 5 predictions! We&#8217;ll look at the top games of the day and what that means for our favorite CFB picks and player props. Check our NCAAF News Hub for all things Week 5! College Football Week 5 Predictions &amp; Preview We\u2019re into Week 5\u2014the last weekend of September\u2014and while&hellip;<\/p>\n","protected":false},"author":69,"featured_media":239359,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"footnotes":""},"categories":[5],"tags":[17],"league":[116],"class_list":["post-239355","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-ncaaf","league-ncaaf"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.6 (Yoast SEO v26.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>College Football Week 5 Picks: Preview and Expert Predictions<\/title>\n<meta name=\"description\" content=\"Props expert Sam Pasco brings you our College Football Week 4 predictions, featuring notable games, odds, and expert picks and predictions!\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/props.com\/cfb-week-5-picks-expert-predictions-preview\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CFB Week 5 Predictions: Expert Picks &amp; 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